Accurate-mass constrained de novo interpretation
adjacent · Constrained search
Accurate-mass constrained de novo interpretation: adjacent · Constrained search. Uses 10 ppm parent-mass accuracy plus immonium-ion composition to replace the database with the set of sequence permutations the mass allows, then feeds the resulting…
Uses 10 ppm parent-mass accuracy plus immonium-ion composition to replace the database with the set of sequence permutations the mass allows, then feeds the resulting de novo sequences into a similarity search. An early statement of the hybrid de novo plus homology strategy.
| Kind | adjacent |
| Family | Constrained search |
| Deep learning | no |
| Acquisition | DDA |
Papers
- Role of Accurate Mass Measurement (±10 ppm) in Protein Identification Strategies Employing MS or MS/MS and Database Searching (1999, Analytical Chemistry, peer-reviewed)