Alzheimer amino acid substitution pipeline
downstream-application
Alzheimer amino acid substitution pipeline: downstream-application. Bioinformatic pipeline that searches proteomic data for amino acid substitutions using a de novo sequencing assisted strategy, and identifies the substitutions specific…
Bioinformatic pipeline that searches proteomic data for amino acid substitutions using a de novo sequencing assisted strategy, and identifies the substitutions specific to Alzheimer’s disease as candidate biomarkers or therapeutic targets.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | General proteomics |
Paper describing it
- Mapping protein variants associated with Alzheimer’s disease by mass-spectrometry based de novo sequencing assisted strategy (2026, Journal of Alzheimer’s Disease, peer-reviewed)