Amino acid-coded mass tagging
algorithm · Chemical labeling assisted
Amino acid-coded mass tagging: algorithm · Chemical labeling assisted. Codes amino acids by mass before MALDI TOF/TOF so that incomplete CID of singly and doubly charged precursors still yields assignable series, recovering spectra that…
Codes amino acids by mass before MALDI TOF/TOF so that incomplete CID of singly and doubly charged precursors still yields assignable series, recovering spectra that would otherwise go unidentified and making the instrument’s throughput usable for de novo work.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical labeling assisted |
Papers describing it (3)
- Use of Deuterium-Labeled Lysine for Efficient Protein Identification and Peptide de Novo Sequencing (2002, Analytical Chemistry, peer-reviewed)
- Precise peptide sequencing and protein quantification in the human proteome through in vivo lysine-specific mass tagging (2003, Journal of the American Society for Mass Spectrometry, peer-reviewed)
- Enhancing TOF/TOF-based de Novo Sequencing Capability for High Throughput Protein Identification with Amino Acid-Coded Mass Tagging (2005, Journal of Proteome Research, peer-reviewed)