DIY de novo antibody sequencing workflow
algorithm
DIY de novo antibody sequencing workflow: algorithm. Assembled from off-the-shelf parts rather than new software: multi-protease digestion, complementary fragmentation and existing de novo tools, combined into a protocol…
Assembled from off-the-shelf parts rather than new software: multi-protease digestion, complementary fragmentation and existing de novo tools, combined into a protocol that reached complete accuracy across antibody variable regions and decoded an unknown anti-HA antibody.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
Papers
- Do-It-Yourself De Novo Antibody Sequencing Workflow that Achieves Complete Accuracy of the Variable Regions (2025, Journal of Proteome Research, peer-reviewed)