Goat ApoA-I antibody de novo sequencing
downstream-application
Goat ApoA-I antibody de novo sequencing: downstream-application. Replaces a polyclonal reagent with defined monoclonals by de novo sequencing goat antibodies: 15 candidate sequences were recovered, four mixtures formulated, and the…
Replaces a polyclonal reagent with defined monoclonals by de novo sequencing goat antibodies: 15 candidate sequences were recovered, four mixtures formulated, and the four-antibody mixture benchmarked against the polyclonal in an ApoA-I immunoturbidimetric assay over 105 human sera.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Antibodyomics |
Paper describing it
- From polyclonal to monoclonal: de novo sequencing of goat antibodies for a standardized ApoA-I immunoturbidimetric assay (2026, Journal of Biological Engineering, peer-reviewed)