Leucine/isoleucine discrimination
adjacent · Neural network
Leucine/isoleucine discrimination: adjacent · Neural network. Deep-neural-network discrimination of the isomeric residues leucine and isoleucine, which are practically indistinguishable in de novo sequencing from ordinary tandem MS…
Deep-neural-network discrimination of the isomeric residues leucine and isoleucine, which are practically indistinguishable in de novo sequencing from ordinary tandem MS data. Rather than relying on the characteristic satellite ions that EThCD fragmentation produces, it learns from raw spectra directly, searching a broader range of the signal for other evidence that separates the two.
| Kind | adjacent |
| Family | Neural network |
| Deep learning | yes |
| Acquisition | DDA |