PASEF sequence confirmation and de novo
algorithm
PASEF sequence confirmation and de novo: algorithm. Uses PASEF on a timsTOF to accelerate the multi-protease digests (trypsin, elastase, chymotrypsin) that confirm a biopharmaceutical sequence, with data clean enough to…
Uses PASEF on a timsTOF to accelerate the multi-protease digests (trypsin, elastase, chymotrypsin) that confirm a biopharmaceutical sequence, with data clean enough to drive de novo sequencing as well.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
Paper describing it
- Use of PASEF for Accelerated Protein Sequence Confirmation and De Novo Sequencing with High Data Quality (2022, Methods in Molecular Biology, peer-reviewed)