RNovA

algorithm · Transformer (AR)

RNovA: algorithm · Transformer (AR). Zero-shot open PTM discovery

Zero-shot open PTM discovery

Kind	algorithm
Family	Transformer (AR)
Deep learning	yes
Acquisition	DDA

Code

• https://github.com/zqq66/RNovA
• https://github.com/AmadeusloveIris/RNovA_SeqFiller_Inference

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Papers

• Zero-shot de novo peptide sequencing with open posttranslational modification discovery (2026, Nature Biotechnology, peer-reviewed)
• Zero-Shot De Novo Peptide Sequencing with Open Post-Translational Modification Discovery (2025, Research Square, preprint)

Authors (11)

Zeping Mao, Chao Peng, Yuling Chen, Ping Wu, Qianqiu Zhang, Lei Xin, Haiteng Deng, Ming Li, Yonghan Yu, Ruixue Zhang, Baozhen Shan

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