InstaNovo-FM training corpus

training · DDA · 4 versions

Tandem mass spectra with PSM labels, uniformly reprocessed from public PRIDE submissions to pretrain and evaluate InstaNovo-FM. The largest labelled corpus published in this field.
Kind training
Acquisition DDA
Organisms mixed
Home https://huggingface.co/datasets/InstaDeepAI/InstaNovo

Tandem mass spectra with PSM labels, uniformly reprocessed from public PRIDE submissions to pretrain and evaluate InstaNovo-FM. The largest labelled corpus published in this field.

Versions

LCFM (low confidence)

The broadest and least stringently filtered labelled tier, from which the stricter ones are derived. “Low” is relative to the other tiers, not absolute: every labelled tier is high-confidence PSMs.

released 2026-09-03 · introduced by InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments

Where it lives:

MCFM (medium confidence)

A stricter PSM filter than LCFM, and a superset of HCFM.

released 2026-09-03 · introduced by InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments

Where it lives:

HCFM (high confidence)

The most stringently filtered tier, a subset of both others.

released 2026-09-03 · introduced by InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments

Where it lives:

ACFM (all confidence)

The unlabelled all-confidence superset the three labelled tiers are filtered out of. Not published as a processed tier, but reproducible: the InstaNovo-FM paper lists the 92 raw accessions it was built from in its Supplementary Table S1, recorded here as provenance, so rebuilding it means reprocessing those rather than downloading it.

released 2026-09-03 · introduced by InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments

Assembled from 92 third-party submissions:

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