Method for protein identification from tandem mass spectral employing both spectrum comparison and de novo sequencing for biomedical applications
US20050074816A1 · Individual · priority 2003
| Patent | US20050074816A1 ↗ |
| Status | Abandoned |
| Priority date | 2003-07-07 |
| Filed | 2004-07-07 |
| Published | 2005-04-07 |
| Assignee | Individual |
| Current assignee | University of Colorado Boulder |
Abstract
A method and algorithm for identifying a protein sequence from mass spectral data combines peptide spectrum matching analysis or spectrum comparison approaches and de novo sequencing approaches. The algorithm of the invention identifies peptide sequences determined independently by each approach, then compares the results and assigns a score reflecting the “goodness” of the match with a full-length protein sequence. Because peptides are identified using independent approaches, the probability of a correct match is increased.
Why it is here
Mark Duncan: protein identification scoring peptides found by both database matching and de novo sequencing. Abandoned application.
Inventors (3)
Mark Duncan, Srdjan Askovic, Kim Fung
An inventor links to an author page only where the same person is evident, never on a name alone.
Catalogued patents it cites (1)
- US6829539B2 Methods for quantification and de novo polypeptide sequencing by mass spectrometry
Cited by (2 patent families, 2 organisations)
- Coon Joshua J company: US20090173878A1
- Wisconsin Alumni Research Foundation academic: US8742333B2
Every family, of any applicant, that cites this one, as Google Patents lists them; an assignee is given its English name.