Peptide sequencing from peptide fragmentation mass spectra
US7783429B2 · Charité – Universitätsmedizin Berlin · priority 2005
| Patent | US7783429B2 ↗ |
| Status | Expired - Fee Related |
| Priority date | 2005-02-18 |
| Filed | 2005-02-18 |
| Published (granted) | 2010-08-24 |
| Assignee | Charité – Universitätsmedizin Berlin |
| Also published as | US20060190183A1 |
Abstract
The invention relates to a method of peptide sequencing from peptide fragment mass data, wherein a plurality of candidate peptide sequences are determined comprises the steps of: calculating peptide fragment masses, searching a plurality of peak data for masses matching said calculated peptide fragment masses, annotating all permutations of said peak data with amino acid sequences that correspond to the calculated peptide fragment masses, extending said potential sequences to resulting masses with additional matching masses, extending stepwise additions until the resulting masses correspond to parental peptide masses or said parental peptide masses minus the mass of water, and identifying at least one peptide sequence by deleting sequences that can not be extended to endpoints of said parental peptide masses, and deleting identical sequences generated.
Why it is here
Charite Berlin: candidate sequences derived from fragment masses, then ranked by comparing their computed spectra with the data.
Inventors (2)
An inventor links to an author page only where the same person is evident, never on a name alone.
Catalogued papers it cites (1)
- Sequence database searches via de novo peptide sequencing by tandem mass spectrometry (1997) added by the examiner
Matched from the patent’s 1 literature citations by the rules the paper citation graph uses.
Catalogued patents it cites (1)
- US6582965B1 Method for de novo peptide sequence determination
Cited by catalogued patents (1)
- RU2843981C1 Method for de novo sequencing of amino acid sequences
Cited by (3 patent families, 3 organisations)
- George Washington University academic: US8901487B2
- Integrated Dna Technologies company: US7604998B2
- 国家电网公司 company: CN104281130B
Every family, of any applicant, that cites this one, as Google Patents lists them; an assignee is given its English name.