XA-Novo: an accurate and high-throughput mass spectrometry-based de novo sequencing technology for monoclonal antibodies and antibody mixtures

preprint · Research Square · 2025

preprint · Research Square · 2025. Yueting Xiong et al.
Date 2025-02-07
Type preprint
Venue Research Square
Publisher Research Square
Contribution algorithm
DOI 10.21203/rs.3.rs-5858891/v1
Citations (OpenAlex) 3

Peer-reviewed version: XA-Novo: an accurate and high-throughput mass spectrometry-based de novo sequencing technology for monoclonal antibodies and antibody mixtures (2026-02-15, Nature Communications)

Authors

  1. Yueting Xiong · Xiamen University, Xiang An Biomedicine Laboratory
  2. Wenbin Jiang · Xiamen University
  3. Jin Xiao · Xiamen University
  4. Qingfang Bu · Xiamen University
  5. Jingyi Wang · Xiamen University, Xiang An Biomedicine Laboratory
  6. Zhenjian Jiang · Fudan University
  7. Ling Luo · Xiamen University
  8. Xiaoqing Chen · Xiamen University
  9. Yijie Qiu · Xiang An Biomedicine Laboratory
  10. Yangtao Wu · Xiamen University
  11. Fan Liu · Xiang An Biomedicine Laboratory
  12. Rongshan Yu · Aginome Scientific, Xiamen University
  13. Ning-Shao Xia · Xiamen University
  14. Quan Yuan · Xiamen University

Methods and tools

  • XA-Novo: NAR knowledge distillation

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