Plant-pathogen effectors

2 workflows · 2004–2010

Plant-pathogen effectors: Effector proteins secreted by plant pathogens, often from organisms with no usable reference. 2 catalogued workflows and 2 papers.

Effector proteins secreted by plant pathogens, often from organisms with no usable reference.

Workflows 2
Papers 2
Authors 11
Active 2004-01-01 to 2010-05-10

Workflows (2)

  • High plains disease agent characterization (2004): Downstream application of de novo peptide sequencing to an unidentified plant pathogen. The 32-kDa protein specific to high plains disease was sequenced by time-of-flight MS after the agent was isolated in pure culture by vascular puncture inoculation. De novo sequencing of peptides from proteolytic digests of the SDS-PAGE band corrected the public record: the GenBank nucleotide-derived sequence U60141, deposited as the probable N-protein of high plains virus, turned out to be incomplete, and 18 further residues were found at the N terminus. BLAST then returned no significant homology to any protein in the databases, indicating a hitherto unclassified virus group. A clean early demonstration of why de novo matters: the answer was unreachable by database search because the correct sequence was not in any database.
  • Plasmopara elicitor de novo workflow (2010): Downstream application combining de novo peptide sequencing algorithms with RACE-PCR to identify a Plasmopara halstedii elicitor protein.

Papers (2)

Authors (11)

Alfred Nordheim, Claudia Fladerer, Dallas L. Seifers, Frank Braendle, Johannes Madlung, Kenneth G. Standing, Otmar Spring, Stephan Jung, Steve Haber, Werner Ens, Yi-Min She

Where the work happened

Canada, Germany, USA

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