3D OrbiSIMS in situ protein identification
downstream-application
3D OrbiSIMS in situ protein identification: downstream-application. Gas cluster ion beam SIMS with Orbitrap analysis fragments surface proteins in situ, and de novo peptide sequencing annotates 16 proteins, enabling protein imaging and…
Gas cluster ion beam SIMS with Orbitrap analysis fragments surface proteins in situ, and de novo peptide sequencing annotates 16 proteins, enabling protein imaging and depth profiling in skin.
| Kind | downstream-application |
| Acquisition | DDA |
| Application area | General proteomics |
Paper describing it
- Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling (2020, Nature Communications, peer-reviewed)