Anti-MUC1 139H2 reverse engineering
downstream-application
Anti-MUC1 139H2 reverse engineering: downstream-application. Reverse-engineers the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing, MUC1 being a mucin whose aberrant expression and glycosylation matter in…
Reverse-engineers the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing, MUC1 being a mucin whose aberrant expression and glycosylation matter in adenocarcinoma.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Antibodyomics |
Data
What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.
Evaluated on
Deposited
- Sequencing the anti-MUC1 hybridoma antibody 139H2 (as deposited) · 2023 preprint, 2024 peer-reviewed
Also used, purpose not recorded
- Anti-FLAG-M2 antibody sequencing (as deposited) · 2024 thesis
- Bottom-up data - sequencing (as deposited) · 2024 thesis
- Direct mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum (as deposited) · 2024 thesis
- Sequencing the anti-MUC1 hybridoma antibody 139H2 (as deposited) · 2024 thesis
- Template-based assembly of proteomic short reads for de novo antibody sequencing and repertoire profiling (as deposited) · 2024 thesis
Papers describing it (3)
- Reverse engineering the anti-MUC1 hybridoma antibody 139H2 by mass spectrometry-based de novo sequencing (2023, bioRxiv, preprint)
- De novo antibody sequencing based on mass spectrometry (2024, thesis)
- Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry–based de novo sequencing (2024, Life Science Alliance, peer-reviewed)