Bat MHC I peptidome
downstream-application
Bat MHC I peptidome: downstream-application. Crystal structures of Pteropus alecto MHC I plus de novo LC-MS/MS of peptides eluted from a random library exchange show a bat-specific three-residue insertion promotes…
Crystal structures of Pteropus alecto MHC I plus de novo LC-MS/MS of peptides eluted from a random library exchange show a bat-specific three-residue insertion promotes high-affinity peptide binding.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Immunopeptidomics / neoantigen |
Paper describing it
- Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding (2019, The Journal of Immunology, peer-reviewed)