CDR peptide biomarker sequencing
downstream-application
CDR peptide biomarker sequencing: downstream-application. Tests detection of specific antibody CDR peptides in serum IgG backgrounds by Orbitrap MS, de novo sequencing half of the detectable adalimumab CDR peptides at attomole…
Tests detection of specific antibody CDR peptides in serum IgG backgrounds by Orbitrap MS, de novo sequencing half of the detectable adalimumab CDR peptides at attomole levels.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Antibodyomics |
Paper describing it
- An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions (2011, Analytical and Bioanalytical Chemistry, peer-reviewed)