De novo assisted search for nonspecific phosphopeptides
algorithm · Hybrid de novo + database search
De novo assisted search for nonspecific phosphopeptides: algorithm · Hybrid de novo + database search. Makes broad-specificity proteases usable in phosphoproteomics: a conventional database search cannot identify phosphopeptides without enzyme…
Makes broad-specificity proteases usable in phosphoproteomics: a conventional database search cannot identify phosphopeptides without enzyme specificity, so de novo sequencing proposes the sequence and the search confirms it.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Hybrid de novo + database search |
Paper describing it
- Identification of phosphopeptides with unknown cleavage specificity by a de novo sequencing assisted database search strategy (2014, PROTEOMICS, peer-reviewed)