DIANovo
algorithm · Transformer (AR)
Transformer-based de novo sequencer for DIA: disentangles coeluted/multiplexed precursor spectra. Presented in Zheng Ma’s arXiv preprint (2024) and his PhD thesis (2025).
| Kind | algorithm |
| Deep learning | yes |
| Acquisition | DIA |
| Family | Transformer (AR) |
Code
Live stars, open issues and last-push figures are on the Code activity chart.
Checkpoints
| Version | Trained on | Host | Licence | Size | Checked | Backup |
|---|---|---|---|---|---|---|
| GNova-Astral_pretrain | — | git-LFS | Apache-2.0 | 516 MB | verified 2026-10-02 | copy |
| RGNova-Astral_op | — | git-LFS | Apache-2.0 | 2.1 GB | verified 2026-10-02 | copy |
| RGNova-Astral_sg | — | git-LFS | Apache-2.0 | 2.1 GB | verified 2026-10-02 | copy |
A host marked archival has a DOI and keeps what it is given. The others can move or disappear, which is why they are checked rather than merely listed. verified means the bytes were fetched and hashed on the date shown; live means only that the host answered when last asked. Where a copy is linked, it is a backup of someone else’s weights kept in case the original link goes stale; the original is the link to cite and to prefer.
Data
What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.
Trained on
- DIA_urine_proteomics_biomarker_discovery_abdominal-pain (as deposited) · 2024 preprint, 2025 thesis
- Evaluating the influence of MS-acquisition parameters on DDA label-free proteomics analyses (as deposited) · 2024 preprint, 2025 thesis
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-ind (PXD046386) (as deposited) · 2024 preprint, 2025 thesis
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-ind (PXD046444) (as deposited) · 2024 preprint, 2025 thesis
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition (as deposited) · 2024 preprint, 2025 thesis
- Untargeted data independent acquisition proteomics analysis using Orbitrap mass spectrometers and DIA-Umpire (as deposited) · 2024 preprint, 2025 thesis
Evaluated on
- Chorus project 1105 (as deposited) · 2024 preprint, 2025 thesis
- Evaluating the influence of MS-acquisition parameters on DDA label-free proteomics analyses (as deposited) · 2024 preprint, 2025 thesis
- Narrow-window DIA: Ultra-fast quantitative analysis of comprehensive proteomes with high sequencing depth. Dilution Seri (as deposited) · 2024 preprint, 2025 thesis
- PXD026600 (as deposited) · 2024 preprint, 2025 thesis
- PXD046471 (as deposited) · 2024 preprint, 2025 thesis
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-ind (PXD046386) (as deposited) · 2024 preprint, 2025 thesis
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition (as deposited) · 2024 preprint, 2025 thesis
Also used, purpose not recorded
- A systematic screening pipeline identifies a new regulator of tyrosinated microtubule dynamics (as deposited) · 2025 thesis
- An Unbiased Strategy for Selecting Effective Combinations of Therapeutic Targets Supports the Development of a Novel Bis (as deposited) · 2025 thesis
- Combined Protein Signature of ALDH1A1, LGALS3, LGALS3BP Predicts Cancer Recurrence Post-Liver Transplantation Beyond Mil (as deposited) · 2025 thesis
- Investigation of the arsenic regulated proteome of PML bodies (as deposited) · 2025 thesis
- Kinobead profiling of PITCOINs1-3 (as deposited) · 2025 thesis
- PXD036171 (as deposited) · 2025 thesis
- Protein markers in Oral Squamous Cell Carcinoma (OSCC) (as deposited) · 2025 thesis
- Proteomics Analysis of Trop2 Xenograft Prostate Tumors (as deposited) · 2025 thesis
- Proteomics analysis of amyloid corneal aggregates from lattice corneal dystrophy patients (as deposited) · 2025 thesis
- Proteomics investigation of Nucleostemin role in Nucleo-phosmin mutated OCI-AML 3 cell line (as deposited) · 2025 thesis
- Response Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic p (as deposited) · 2025 thesis
- SARS-CoV-2 ORF8 interactome in the secretory pathway (as deposited) · 2025 thesis
- SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription (as deposited) · 2025 thesis
- Structural analysis of neurofibromin by crosslinking mass spectrometry (as deposited) · 2025 thesis
- Targeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasive (PXD005388) (as deposited) · 2025 thesis
- Targeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- whole cell lys (as deposited) · 2025 thesis
- ¬The EGFR/ErbB inhibitor neratinib promotes apoptosis and clearance by airway macrophages (as deposited) · 2025 thesis