DIAVariant

algorithm · Homology search

DIAVariant: algorithm · Homology search. Identifies peptide sequence variants directly from DIA spectra by de novo sequencing-assisted homology search, with rigorous FDR control, so variant peptides outside the…

Identifies peptide sequence variants directly from DIA spectra by de novo sequencing-assisted homology search, with rigorous FDR control, so variant peptides outside the database can be found without a DDA library.

Kind	algorithm
Acquisition	DIA
Family	Homology search

Paper describing it

• De Novo sequencing-assisted homology search for DIA data analysis enables low abundance peptide variants discovery (2025, bioRxiv, preprint)

Authors (5)

Rui Qiao, Hechen Li, Haibo Bian, Lei Xin, Baozhen Shan

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