Lys-Sequencer

algorithm · Spectra pair

Lys-Sequencer: algorithm · Spectra pair. Database-independent de novo sequencing from paired Lys-C and Lys-N digests, whose single-residue-transposed peptides yield complementary high-resolution spectra, with…

Database-independent de novo sequencing from paired Lys-C and Lys-N digests, whose single-residue-transposed peptides yield complementary high-resolution spectra, with residue-level confidence reported per call.

Kind	algorithm
Family	Spectra pair
Deep learning	no
Acquisition	DDA

Papers

• Lys-Sequencer: An algorithm for de novo sequencing of peptides by paired single residue transposed Lys-C and Lys-N digestion coupled with high-resolution mass spectrometry (2020, Rapid Communications in Mass Spectrometry, peer-reviewed)

Authors (3)

Yuan Mao, Thomas J. Daly, Ning Li (Tarrytown)

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• The architectures

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