π-HelixNovo2

algorithm · Transformer (AR)

π-HelixNovo2: algorithm · Transformer (AR). Successor to π-HelixNovo with an emphasis on availability: an online inference service alongside the model architecture refinement. Same Tsinghua / Pengcheng Lab / NCPSB…

Successor to π-HelixNovo with an emphasis on availability: an online inference service alongside the model architecture refinement. Same Tsinghua / Pengcheng Lab / NCPSB collaboration as the original.

Kind	algorithm
Family	Transformer (AR)
Deep learning	yes
Acquisition	DDA

Code

• https://openi.pcl.ac.cn/OpenI/pi-HelixNovo-NPU

Not tracked on the Code activity chart: those figures come from the GitHub API, and this link is not a public GitHub repository.

Papers

• π-HelixNovo2: Making Accurate Online De Novo Peptide Sequencing Available to All (2026, Genomics, Proteomics & Bioinformatics, peer-reviewed)

Authors (12)

Tingpeng Yang, Tianze Ling, Boyan Sun, Zhendong Liang, Cheng Lai, Jiangli Hu, Zexuan Yi, Yonghong He, Leyuan Li, Yue Yu, Cheng Chang, Yu Wang

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• The architectures
• Models and the authors behind them

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