Proteasomal spliced peptide estimation

downstream-application

Proteasomal spliced peptide estimation: downstream-application. Uses de novo sequencing of HLA-I peptide spectra, filtered against UniProt and matched to spliced candidates, to estimate how many ligands are proteasome-spliced.

Uses de novo sequencing of HLA-I peptide spectra, filtered against UniProt and matched to spliced candidates, to estimate how many ligands are proteasome-spliced.

Kind	downstream-application
Deep learning	no
Acquisition	DDA
Application area	Immunopeptidomics / neoantigen

Data

What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.

Deposited

• Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome (as deposited) · 2018 peer-reviewed, 2018 preprint

Also used, purpose not recorded

• Fully unsupervised identification of HLA-I motifs (as deposited) · 2018 peer-reviewed, 2018 preprint

Papers describing it (2)

• Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome (2018, bioRxiv, preprint)
• Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome* (2018, Molecular & Cellular Proteomics, peer-reviewed)

Authors (10)

Roman Mylonas, Ilan Beer, Christian Iseli, Chloe Chong, Hui-Song Pak, David Gfeller, George Coukos, Ioannis Xenarios, Markus Müller, Michal Bassani-Sternberg

Seen in the charts

• Application areas

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