Proteasomal spliced peptide estimation
downstream-application
Proteasomal spliced peptide estimation: downstream-application. Uses de novo sequencing of HLA-I peptide spectra, filtered against UniProt and matched to spliced candidates, to estimate how many ligands are proteasome-spliced.
Uses de novo sequencing of HLA-I peptide spectra, filtered against UniProt and matched to spliced candidates, to estimate how many ligands are proteasome-spliced.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Immunopeptidomics / neoantigen |
Papers describing it (2)
- Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome (2018, bioRxiv, preprint)
- Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome* (2018, Molecular & Cellular Proteomics, peer-reviewed)