QUORUM
post-processor · Gradient boosting
QUORUM: post-processor · Gradient boosting. Consensus de novo caller with FDR control: runs Casanovo, InstaNovo and PrimeNovo on the same spectrum, scores every aligned residue with a gradient-boosted model from…
Consensus de novo caller with FDR control: runs Casanovo, InstaNovo and PrimeNovo on the same spectrum, scores every aligned residue with a gradient-boosted model from inter-model agreement, ion evidence class and retention-time error, assembles a fourth candidate and picks among the four with a logistic-regression selector.
| Kind | post-processor |
| Deep learning | no |
| Acquisition | DDA |
| Family | Gradient boosting |
Paper describing it
- Can we Confidently Sequence the „Peptide Dark Matter“? Reaching a Consensus for De Novo Peptide Sequencing (2026, Proceedings of the 38th European Peptide Symposium, presentation)