sORF noncanonical MHC-I peptides

downstream-application

sORF noncanonical MHC-I peptides: downstream-application. Combines Ribo-seq-derived sORF databases with database search and de novo sequencing to identify 308 noncanonical MHC class I peptides from two tumor cell lines.

Combines Ribo-seq-derived sORF databases with database search and de novo sequencing to identify 308 noncanonical MHC class I peptides from two tumor cell lines.

Kind	downstream-application
Deep learning	no
Acquisition	DDA
Application area	Immunopeptidomics / neoantigen

Data

What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.

Deposited

• Discovery of Non-Canonical Peptides Derived from Novel Small Open Reading Frames as MHC-I Epitopes (as deposited)

Paper describing it

• An Integrated Approach for Discovering Noncanonical MHC-I Peptides Encoded by Small Open Reading Frames (2021, Journal of the American Society for Mass Spectrometry, peer-reviewed)

Authors (9)

Lei Chen, Yuanliang Zhang, Ying Yang, Yang Yang (Hong Kong Polytechnic University), Huihui Li, Xuan Dong, Hongwei Wang, Zhi Xie, Qian Zhao

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