Stitch

post-processor · Sequence assembly

Stitch: post-processor · Sequence assembly. Assembles de novo peptides from Casanovo, PEAKS, pNovo and MaxNovo into full antibody sequences, and corrects the two error classes that assembly alone cannot: mass…

Assembles de novo peptides from Casanovo, PEAKS, pNovo and MaxNovo into full antibody sequences, and corrects the two error classes that assembly alone cannot: mass coincidences, where a different residue combination matches the same mass, and I/L ambiguity.

Kind	post-processor
Family	Sequence assembly
Deep learning	no
Acquisition	DDA

Code

• https://github.com/snijderlab/stitch

Live stars, open issues and last-push figures are on the Code activity chart.

Papers

• A Handle on Mass Coincidence Errors in De Novo Sequencing of Antibodies by Bottom-up Proteomics (2024, Journal of Proteome Research, peer-reviewed)

Authors (2)

Douwe Schulte, Joost Snijder

Seen in the charts

• The architectures
• Code activity
• Models and the authors behind them

Back to the full map