Top-down tandem spectrum de novo sequencing
algorithm
Top-down tandem spectrum de novo sequencing: algorithm. De novo sequencing of top-down tandem mass spectra, aimed at the proteins no database can serve – organisms with unknown genomes, antibodies, novel splice variants –…
De novo sequencing of top-down tandem mass spectra, aimed at the proteins no database can serve – organisms with unknown genomes, antibodies, novel splice variants – and at recovering a complete sequence rather than peptide-length fragments.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
Paper describing it
- De Novo Sequencing of Top-Down Tandem Mass Spectra: A Next Step towards Retrieving a Complete Protein Sequence (2017, Proteomes, peer-reviewed)