Hybrid search
3 methods · 2005–2013
Hybrid search: De novo interpretation used to drive a database search: the sequence or the tag read from the spectrum becomes the query, rather than the database enumerating candidates to score.
De novo interpretation used to drive a database search: the sequence or the tag read from the spectrum becomes the query, rather than the database enumerating candidates to score.
The earliest of its 3 methods is DeNovoID (2005); 2 more have followed.
| Methods | 3 |
| Papers describing them | 3 |
| Authors | 9 |
| Active | 2005-07-01 to 2013-01-21 |
| Kinds | adjacent (3) |
| Acquisition | DDA (3) |
Methods (3)
Oldest first, by the paper that describes each one.
- DeNovoID (2005): Web-based tool for identifying peptides from sequence and mass tags deduced from de novo peptide sequencing.
- Lookup Peaks (2007): Hybrid de novo sequencing and database-search method for protein identification by tandem MS.
- NovoDB (2013): Protein identification method integrating de novo sequencing with database searching.
Papers describing them (3)
- DeNovoID: a web-based tool for identifying peptides from sequence and mass tags deduced from de novo peptide sequencing by mass spectroscopy (2005, Nucleic Acids Research, peer-reviewed)
- Lookup Peaks: A Hybrid of de Novo Sequencing and Database Search for Protein Identification by Tandem Mass Spectrometry (2007, Analytical Chemistry, peer-reviewed)
- Mass spectrometry-based protein identification by integrating de novo sequencing with database searching (2013, BMC Bioinformatics, peer-reviewed)