Method for free radical initiated peptide sequencing
US8034623B2 · Sogang University · priority 2009
| Patent | US8034623B2 ↗ |
| Status | Expired - Fee Related |
| Priority date | 2009-01-12 |
| Filed | 2009-10-14 |
| Published (granted) | 2011-10-11 |
| Assignee | Sogang University (printed Industry University Cooperation Foundation of Sogang University) |
| Also published as | CN101775006A, CN101775006B, GB0918091D0, GB2466859A, GB2466859B, KR101063981B1, KR20100083072A, US20100240139A1 |
Abstract
The present invention relates to a free radical initiator and a method for peptide sequencing using the same. Compared with diazo or peroxy functionalized precursors, the precursors using the present compounds are chemically more robust and can generate radical species by homolytic cleavage upon thermal activation, enabling sequencing of a wider variety of peptides. In addition, the present invention makes it feasible to sequence peptides carrying disulfide bonds.
Why it is here
Sogang University: free-radical initiator reagents and a method of peptide sequencing by free-radical initiated fragmentation.
Inventors (4)
Han Bin Oh, Bong-jin Moon, Min-Hyuck Kang, Min-Hee Lee
An inventor links to an author page only where the same person is evident, never on a name alone.
Cited by catalogued patents (2)
- KR101500488B1 One-Step Free Radical-Initiated Peptide Sequencing Mass Spectrometry Using Negative-ion Mode
- KR101658164B1 Free Radical-Initiated Peptide Sequencing Mass Spectrometry Using Bromine Isotopic Signature
Cited by (6 patent families, 5 organisations)
- Sogang University academic: KR101500488B1, KR101658164B1
- DH Technologies Development company: EP4405687A1
- North Carolina State University academic: WO2014093196A1
- 株式会社岛津制作所 company: CN119072628A
- 서강대학교 산학협력단 academic: KR102582698B1
Every family, of any applicant, that cites this one, as Google Patents lists them; an assignee is given its English name.