Automated mAb de novo (Bandeira SPS)
downstream-application · Spectral assembly
Automated mAb de novo (Bandeira SPS): downstream-application · Spectral assembly. Landmark Nat Biotech 2008 paper by Bandeira, Pham, Pevzner, Arnott & Lill: applies Shotgun Protein Sequencing (SPS), that is MS/MS spectral assembly, end-to-end to a…
Landmark Nat Biotech 2008 paper by Bandeira, Pham, Pevzner, Arnott & Lill: applies Shotgun Protein Sequencing (SPS), that is MS/MS spectral assembly, end-to-end to a monoclonal antibody, recovering both chains without any prior sequence.
| Kind | downstream-application |
| Family | Spectral assembly |
| Deep learning | no |
| Acquisition | DDA |
| Application area | antibodyomics |
Papers
- Automated de novo protein sequencing of monoclonal antibodies (2008, Nature Biotechnology, peer-reviewed)