C-terminal ANSA derivatization for negative-ion de novo sequencing
algorithm · Chemical derivatization assisted
C-terminal ANSA derivatization for negative-ion de novo sequencing: algorithm · Chemical derivatization assisted. Derivatizes the peptide C-terminus with 4-aminonaphthalenesulfonic acid so high-energy negative-ion CID gives only C-terminal fragment…
Derivatizes the peptide C-terminus with 4-aminonaphthalenesulfonic acid so high-energy negative-ion CID gives only C-terminal fragment ions, which can be read de novo.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical derivatization assisted |
Paper describing it
- De novo sequencing of proteolytic peptides by a combination of C-terminal derivatization and nano-electrospray/ collision-induced dissociation mass spectrometry (2000, Journal of the American Society for Mass Spectrometry, peer-reviewed)