CDR3 sequence-ladder IgG de novo sequencing
downstream-application
CDR3 sequence-ladder IgG de novo sequencing: downstream-application. Favours selective, high-quality fragmentation over sequence coverage to produce sequence ladders through IgG CDR3 regions, so the variable regions can be read de novo.
Favours selective, high-quality fragmentation over sequence coverage to produce sequence ladders through IgG CDR3 regions, so the variable regions can be read de novo.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Antibodyomics |
Paper describing it
- Selectivity over coverage in de novo sequencing of IgGs (2020, Chemical Science, peer-reviewed)