CHASE
algorithm · Chemical derivatization assisted
CHASE: algorithm · Chemical derivatization assisted. Charge Assisted Sequencing Engine: derivatizes tryptic peptides at the N-terminus with a negatively charged reagent, reads the resulting PSD/TOF-TOF spectra de novo and…
Charge Assisted Sequencing Engine: derivatizes tryptic peptides at the N-terminus with a negatively charged reagent, reads the resulting PSD/TOF-TOF spectra de novo and passes sequences to BLAST.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical derivatization assisted |
Paper describing it
- CHASE, a charge‐assisted sequencing algorithm for automated homology‐based protein identifications with matrix‐assisted laser desorption/ionization time‐of‐flight post‐source decay fragmentation data (2005, Journal of Mass Spectrometry, peer-reviewed)