CNBr ring-opening of cyclic OBOC peptides
adjacent · Chemical derivatization assisted
CNBr ring-opening of cyclic OBOC peptides: adjacent · Chemical derivatization assisted. Places methionine in the macrocycle and linker so cyanogen bromide linearises and releases cyclic library peptides, which are then sequenced manually and with de…
Places methionine in the macrocycle and linker so cyanogen bromide linearises and releases cyclic library peptides, which are then sequenced manually and with de novo software.
| Kind | adjacent |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical derivatization assisted |
Paper describing it
- Practical Ring-Opening Strategy for the Sequence Determination of Cyclic Peptides from One-Bead-One-Compound Libraries (2013, ACS Combinatorial Science, peer-reviewed)