Conus zonatus single-disulfide conopeptide Czon1107

downstream-application

Conus zonatus single-disulfide conopeptide Czon1107: downstream-application. Identifies and de novo sequences single-disulfide conopeptides from Conus zonatus and Conus caracteristicus venom using MSn of native and derivatized peptides, then…

Identifies and de novo sequences single-disulfide conopeptides from Conus zonatus and Conus caracteristicus venom using MSn of native and derivatized peptides, then shows Czon1107 allosterically inhibits human nicotinic receptors.

Kind	downstream-application
Deep learning	no
Acquisition	DDA
Application area	Venomics

Data

What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.

Deposited

• Identification and characterization of novel peptide components in the venom of Indian marine cone snails (as deposited)

Paper describing it

• Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors (2020, Journal of Biological Chemistry, peer-reviewed)

Authors (7)

Madhan Kumar Mohan, Nikita Abraham, R.P. Rajesh, Jayaseelan B. Franklin, Lotten Ragnarsson, Richard J. Lewis, Siddhartha P. Sarma

Seen in the charts

• Application areas
• Models and the authors behind them

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