Conus zonatus single-disulfide conopeptide Czon1107
downstream-application
Conus zonatus single-disulfide conopeptide Czon1107: downstream-application. Identifies and de novo sequences single-disulfide conopeptides from Conus zonatus and Conus caracteristicus venom using MSn of native and derivatized peptides, then…
Identifies and de novo sequences single-disulfide conopeptides from Conus zonatus and Conus caracteristicus venom using MSn of native and derivatized peptides, then shows Czon1107 allosterically inhibits human nicotinic receptors.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | Venomics |
Paper describing it
- Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors (2020, Journal of Biological Chemistry, peer-reviewed)