De novo FDR control procedure
post-processor
De novo FDR control procedure: post-processor. False discovery rate control for the de novo setting, where target-decoy competition does not apply: reported to be at least as powerful as database search, with…
False discovery rate control for the de novo setting, where target-decoy competition does not apply: reported to be at least as powerful as database search, with empirical evidence of statistical validity on a set of common de novo applications.
| Kind | post-processor |
| Deep learning | no |
| Acquisition | DDA |
Data
What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.
Also used, purpose not recorded
- A comprehensive LFQ benchmark dataset to validate data analysis pipelines on modern day acquisition strategies in proteo (as deposited)
- A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified pe (as deposited)
- Assessing protein sequence database suitability using de novo sequencing (as deposited)
- PXD066485 (as deposited)
Paper describing it
- A procedure for controlling the false discovery rate of de novo peptide sequencing (2025, bioRxiv, preprint)