De novo SAV discovery
downstream-application
De novo SAV discovery: downstream-application. Discovers single amino-acid variants without SNP databases by pairing de novo sequencing candidates against theoretical proteins, then re-searching to control FDR…
Discovers single amino-acid variants without SNP databases by pairing de novo sequencing candidates against theoretical proteins, then re-searching to control FDR; applied to human brain tissue.
| Kind | downstream-application |
| Deep learning | no |
| Acquisition | DDA |
| Application area | General proteomics |
Paper describing it
- De novo identification and quantification of single amino-acid variants in human brain (2014, Journal of Molecular Cell Biology, peer-reviewed)