Isotope-coded N-terminal sulfonation (ICenS)
algorithm · Chemical labeling assisted
Isotope-coded N-terminal sulfonation (ICenS): algorithm · Chemical labeling assisted. Labels peptides with light or 13C6 heavy 4-sulfophenyl isothiocyanate so the same derivatization yields y-ion dominated spectra for de novo sequencing and isotope…
Labels peptides with light or 13C6 heavy 4-sulfophenyl isothiocyanate so the same derivatization yields y-ion dominated spectra for de novo sequencing and isotope pairs for quantification.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical labeling assisted |
Paper describing it
- Isotope‐coded N‐terminal sulfonation of peptides allows quantitative proteomic analysis with increased de novo peptide sequencing capability (2004, Rapid Communications in Mass Spectrometry, peer-reviewed)