Layered sequence-similarity proteomics
algorithm · Homology search
Layered sequence-similarity proteomics: algorithm · Homology search. Identifies proteins in organisms with unsequenced genomes by layering the search: a stringent database search first, then automated de novo sequencing of what it leaves…
Identifies proteins in organisms with unsequenced genomes by layering the search: a stringent database search first, then automated de novo sequencing of what it leaves behind, then sequence-similarity searching of those de novo reads against related species.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Homology search |
Paper describing it
- Sequence similarity‐driven proteomics in organisms with unknown genomes by LC‐MS/MS and automated <b><i>de novo</i></b> sequencing (2007, PROTEOMICS, peer-reviewed)