Multi-protease dual-fragmentation antibody sequencing

downstream-application · Protease strategy

Multi-protease dual-fragmentation antibody sequencing: downstream-application · Protease strategy. Direct de novo sequencing of monoclonal IgG from the purified product with a panel of complementary proteases and both stepped HCD and EThcD on every…

Direct de novo sequencing of monoclonal IgG from the purified product with a panel of complementary proteases and both stepped HCD and EThcD on every precursor, demonstrated on the anti-FLAG-M2 antibody.

Kind downstream-application
Deep learning no
Acquisition DDA
Family Protease strategy
Application area Antibodyomics

Data

What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.

Evaluated on

Also used, purpose not recorded

Papers describing it (3)

Authors (3)

Weiwei Peng, Matti F Pronker, Joost Snijder

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