Oxazolone C-terminal derivatization
algorithm · Chemical derivatization assisted
Oxazolone C-terminal derivatization: algorithm · Chemical derivatization assisted. Selective C-terminal derivatization, which is hard because C-terminal and side-chain carboxyls behave alike, improved in efficiency and given a bromine signature so…
Selective C-terminal derivatization, which is hard because C-terminal and side-chain carboxyls behave alike, improved in efficiency and given a bromine signature so the C-terminal fragment can be picked out and sequenced.
| Kind | algorithm |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical derivatization assisted |
Paper describing it
- C-terminal de novo sequencing of peptides using oxazolone-based derivatization with bromine signature (2011, Analytical Biochemistry, peer-reviewed)