Protein scaffold filling with a reference

post-processor · Sequence assembly

Protein scaffold filling with a reference: post-processor · Sequence assembly. Fills missing residues in de novo protein scaffolds against a homologous reference to maximise BLOSUM62 score, with exact and greedy algorithms tested on antibodies.

Fills missing residues in de novo protein scaffolds against a homologous reference to maximise BLOSUM62 score, with exact and greedy algorithms tested on antibodies.

Kind	post-processor
Deep learning	no
Acquisition	DDA
Family	Sequence assembly

Papers describing it (3)

• Filling a Protein Scaffold with a Reference (2016, Lecture Notes in Computer Science, peer-reviewed)
• Filling a Protein Scaffold With a Reference (2017, IEEE Transactions on NanoBioscience, peer-reviewed)
• Computational investigation on protein sequencing and genome rearrangement problems (2018, thesis)

Authors (4)

Letu Qingge, Xiaowen Liu, Farong Zhong, Binhai Zhu (Montana State University)

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