Stable isotope N-phosphorylation labeling (SIPL)
adjacent · Chemical labeling assisted
Stable isotope N-phosphorylation labeling (SIPL): adjacent · Chemical labeling assisted. Labels peptide N-termini and lysines with light or heavy phosphoryl groups in a one-pot reaction, improving ionization, strengthening fragment series and giving…
Labels peptide N-termini and lysines with light or heavy phosphoryl groups in a one-pot reaction, improving ionization, strengthening fragment series and giving isotope signatures that ease de novo sequencing and relative quantification.
| Kind | adjacent |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical labeling assisted |
Paper describing it
- Stable Isotope N-Phosphorylation Labeling for Peptide de Novo Sequencing and Protein Quantification Based on Organic Phosphorus Chemistry (2012, Analytical Chemistry, peer-reviewed)