TIPs
downstream-application · Hybrid de novo + database search
TIPs: downstream-application · Hybrid de novo + database search. Deep-learning-guided proteogenomic framework that uses de novo sequencing to refine the search space for transposable-element-derived HLA antigens, finding 20-fold more…
Deep-learning-guided proteogenomic framework that uses de novo sequencing to refine the search space for transposable-element-derived HLA antigens, finding 20-fold more than conventional searches.
| Kind | downstream-application |
| Deep learning | yes |
| Acquisition | DDA |
| Family | Hybrid de novo + database search |
| Application area | Immunopeptidomics / neoantigen |
Data
What the papers describing this method trained it on and reported its results on, as each paper states it. A version is named only where the paper names one.
Also used, purpose not recorded
- non-canonical HLA peptides in cancer (as deposited)
Paper describing it
- TIPs: a deep learning-guided proteogenomic framework to expand the landscape of transposable element-derived antigens with immunopeptidomics (2026, Genome Biology, peer-reviewed)