Expanding the repertoire of conopeptides from the venom of the vermivorous snail Conus regius

peer-reviewed · Toxicon · 2025

peer-reviewed · Toxicon · 2025. Helena B. Fiorotti et al.
Date 2025-08-23
Type peer-reviewed
Venue Toxicon
Publisher Elsevier
Contribution downstream-application
DOI 10.1016/j.toxicon.2025.108551
Citations (OpenAlex) 0

Authors

  1. Helena B. Fiorotti · Butantan Institute
  2. Suely G. Figueiredo · Federal University of Espírito Santo
  3. Emídio Beraldo-Neto · Butantan Institute
  4. Fabiana V. Campos · Federal University of Ouro Preto
  5. Daniel C. Pimenta · Butantan Institute

Methods and tools

  • Conus regius conopeptidome: Reversed-phase LC + Q-TOF MS/MS with Peaks Studio v7 de novo sequencing to identify 520 conopeptides from the vermivorous cone snail Conus regius, spanning 13 conotoxin gene superfamilies and eight disulfide-poor peptide classes: the first molluscan entry in the venomics lane.
  • PEAKS: Commercial DP-based de novo

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