Sequence Determination of a Novel Tripeptide Isolated from the Young Leaves ofAzadirachta indicaA. Juss
peer-reviewed · International Journal of Peptides · 2013
peer-reviewed · International Journal of Peptides · 2013. M. Rajeswari Prabha et al. The neem tree has long been recognized for its unique properties, both against insects and in improving human…
| Date | 2013-02-20 |
| Type | peer-reviewed |
| Venue | International Journal of Peptides |
| Publisher | Wiley |
| Contribution | downstream-application |
| DOI | 10.1155/2013/629549 |
| Citations (OpenAlex) | 3 |
Abstract
The neem tree has long been recognized for its unique properties, both against insects and in improving human health. Every part of the tree has been used as a traditional medicine for household remedy against various human ailments, from antiquity. Although the occurrence of various phytochemicals in neem has been studied, we have identified the presence of a novel tripeptide in the young leaves of neem using a simple and inexpensive paper chromatographic method, detected by Cu(II)-ninhydrin reagent. The peptide nature of the isolated compound is confirmed by spectral studies. The sequence of the peptide is determined using de novo sequencing by tandem MS after purification.
Methods and tools
- Neem leaf tripeptide: Isolates a novel tripeptide from young Azadirachta indica leaves and determines its sequence by de novo MS/MS.