Dual-labeling (guanidination/amidination) de novo sequencing
adjacent · Chemical labeling assisted
Dual-labeling (guanidination/amidination) de novo sequencing: adjacent · Chemical labeling assisted. Derivatizes peptides by guanidination and amidination so mass-coded labels distinguish N- and C-terminal fragment ions and promote informative…
Derivatizes peptides by guanidination and amidination so mass-coded labels distinguish N- and C-terminal fragment ions and promote informative fragmentation for de novo sequencing.
| Kind | adjacent |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical labeling assisted |
Paper describing it
- Peptide de Novo Sequencing Facilitated by a Dual-Labeling Strategy (2005, Analytical Chemistry, peer-reviewed)