Primary sequence determination of a monoclonal antibody against α-synuclein using a novel mass spectrometry-based approach

peer-reviewed · International Journal of Mass Spectrometry · 2012

peer-reviewed · International Journal of Mass Spectrometry · 2012. Eric Sousa et al.
Date 2012-02-01
Type peer-reviewed
Venue International Journal of Mass Spectrometry
Publisher Elsevier BV
Contribution downstream-application
DOI 10.1016/j.ijms.2011.05.005
Citations (OpenAlex) 15

Authors

  1. Eric Sousa · Pfizer (United States)
  2. Stephane Olland · Pfizer (United States)
  3. Heather H. Shih · Pfizer (United States)
  4. Kim Marquette · Pfizer (United States)
  5. Robert Martone · Pfizer (United States)
  6. Zhijian Lu · Pfizer (United States)
  7. Janet Paulsen · Pfizer (United States)
  8. Davinder Gill · Pfizer (United States)
  9. Tao He · Pfizer (United States)

Methods and tools

  • Anti alpha-synuclein mAb sequencing: The primary sequence of a monoclonal antibody against alpha-synuclein was determined de novo by mass spectrometry combining ion-trap CID and HCD fragmentation.

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