Palaeoproteomics

5 workflows · 2016–2026

Palaeoproteomics: Ancient enamel, bone and eggshell, where the proteins are damaged and the species may be extinct. 5 catalogued workflows and 5 papers.

Ancient enamel, bone and eggshell, where the proteins are damaged and the species may be extinct.

Workflows 5
Papers 5
Authors 99
Active 2016-09-27 to 2026-06-02

Workflows (5)

  • Ancient ostrich eggshell proteome (2016): Sequencing of ancient peptides bound to ostrich eggshell mineral surfaces, demonstrating protein survival into deep time (~3.8 million years) via de novo MS/MS workflows.
  • Stephanorhinus enamel proteome (2019): Palaeoproteomic enamel-protein workflow on a 1.77-million-year-old Stephanorhinus tooth from Dmanisi, resolving rhinoceros phylogeny beyond the reach of ancient DNA.
  • Gigantopithecus enamel proteome (2019): Palaeoproteomic de novo workflow that recovered the enamel proteome of a 1.9-million-year-old Gigantopithecus blacki molar from Chuifeng Cave, placing it as an early-diverging pongine.
  • Homo antecessor enamel proteome (2020): Palaeoproteomic de novo + tag-search workflow that recovers enamel proteome from a ~800,000-year-old Homo antecessor tooth and uses the resulting sequences to place the lineage on the hominin tree.
  • Ozboneprot (2026): Workflow for de novo sequencing and validation of bone proteins to support shotgun palaeoproteomics on Australian zooarchaeological and palaeontological samples.

Papers (5)

Authors (99)

Amandus Kwekason, Anders Götherström, Ann Margvelashvili, Anna Fotakis, Anne-Marie Bacon, Aurélien Ginolhac, Beatrice Demarchi, Benedikt M Kessler, Beth Shapiro, Bienvenido Martínez-Navarro, Carles Lalueza-Fox, Christian D. Kelstrup, Chunting Michelle Wang, Colin L Freeman, Cristina Chiva, Curtis W Marean, David Lordkipanidze, David Lyon, Diana Samodova, Eduard Sabidó, Eleftheria Palkopoulou, Enrico Cappellini, Eske Willerslev, Eudald Carbonell, Fabrice Demeter, Fernando Racimo, Frido Welker, Gocha Kiladze, Irina Kirillova, J. Víctor Moreno-Mayar, Jacqueline F Hamilton, James Haile, Jane Thomas-Oates, Jazmín Ramos-Madrigal, Jesper V. Olsen, Jessica Thomas, John H Harding, John Parkington, Jordi Agusti, Jos Woolley, Joseph Boileau, Joshua D. Kapp, José María Bermúdez de Castro, Juan Luis Arsuaga, Julia Lee-Thorp, Julie Wilson, Jürgen Cox, Kirsty Penkman, Liora Kolska Horwitz, Lorenzo Rook, Love Dalén, Luca Pandolfi, Ludovic Orlando, M. Thomas P. Gilbert, Maia Bukhsianidze, Manuel Domínguez-Rodrigo, Marc R. Dickinson, Marc de Manuel, Marcela Sandoval Velasco, Martha Tappen, Martin Kuhlwilm, Martyn W Ward, Marvin D Shaw, María Martinón-Torres, Matthew James Collins, Meaghan Mackie, Michael Chazan, Michaela Ecker, Mikkel-Holger S. Sinding, Molly K Crisp, Morten E. Allentoft, Patrick L. Rüther, Paula Kotli, Pere Gelabert, Peter D. Heintzman, Peter Ditchfield, Petra Gutenbrunner, Ralf-Dietrich Kahlke, Reid Ferring, Roland Kröger, Roman Fischer, Rosa Rakownikow Jersie-Christensen, Ross DE MacPhee, Samantha Presslee, Senthilvel K. S. S. Nathan, Shanlin Liu, Shaun Hall, Shivani Tiwary, Sofia C. Samper Carro, Sue O’Connor, Teresa Roncal-Herrero, Terry Harrison, Thomas W. Stafford, Tomas Marques-Bonet, Vera Weisbecker, Wei Liao, Wei Wang, Yoshan Moodley, Yvonne L. Chan

Where the work happened

Australia, Canada, China, Denmark, France, Georgia, Germany, Greenland, Ireland, Israel, Italy, Luxembourg, Malaysia, Norway, Russia, South Africa, Spain, Sweden, Tanzania, UK, USA

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