Disulfide oxidation for de novo MALDI sequencing
adjacent · Chemical derivatization assisted
Disulfide oxidation for de novo MALDI sequencing: adjacent · Chemical derivatization assisted. Shows that performic acid oxidation of the C-terminal cystine ring in frog skin peptides gives more b and y ions than reduction and alkylation, making…
Shows that performic acid oxidation of the C-terminal cystine ring in frog skin peptides gives more b and y ions than reduction and alkylation, making MALDI de novo sequencing easier.
| Kind | adjacent |
| Deep learning | no |
| Acquisition | DDA |
| Family | Chemical derivatization assisted |
Paper describing it
- Oxidation versus carboxamidomethylation of s-s bond in ranid frog peptides: Pro and contra for de novo MALDI-MS sequencing (2008, Journal of the American Society for Mass Spectrometry, peer-reviewed)